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Posttraumatic Stress Disorder (PTSD)
Treatment Approaches for Trauma

Online Continuing Education Course

Course Description

Posttraumatic Stress Disorder Training. 3.5 contact hour course on understanding the impact of PTSD and trauma. Learn how to be prepared and intervene appropriately. Covers assessment, diagnosis, treatment, and prevention of the disorder. CEU applicable for nursing, occupational therapy, physical therapy, and EMS personnel.

Course Price: $28.00

Contact Hours: 3.5

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Customer Reviews

"This was a very good course—well presented, very clear data and case study information, very informative. Will recommend to peers. " - Patricia, OT in Florida

"The course filled a gap in my knowledge in PTSD. Thank you! " - Duncan, NP in Texas

"This course is well-structured and presented in a logical manner that is complementary to learning. " - Scott, OT in Louisiana

"The case studies were very helpful. " - Jennifer, PTA in Idaho

Accreditation / Approval Information

WEST VIRGINIA NURSES: Take the WV version of this course.

Posttraumatic Stress Disorder (PTSD)
Treatment Approaches for Trauma

LEARNING OUTCOME AND OBJECTIVES:  Upon completion of this course, you will have increased your understanding of posttraumatic stress disorder and ability to intervene appropriately in assessment, diagnosis, treatment, and prevention of the disorder. Specific learning objectives include:

  • Define posttraumatic stress disorder (PTSD).
  • Summarize the epidemiology of posttraumatic stress disorder in the United States.
  • Explain the etiology.
  • Identify risk factors for developing PTSD.
  • Discuss the impact that caring for a person with PTSD has on family, friends, and healthcare providers.
  • Identify the symptoms and diagnostic criteria.
  • Discuss medical and nursing procedures to screen patients when PTSD is suspected.
  • Describe current PTSD treatment modalities.
  • Recognize the principal outcome goals for patients and support persons dealing with PTSD.


The Encyclopedia of Mental Disorders (EMD, 2017) defines posttraumatic stress disorder as “a complex disorder in which the affected person’s memory, emotional responses, intellectual processes, and nervous system have been disrupted by one or more traumatic experiences. It is sometimes summarized as a normal reaction to abnormal events.”

PTSD is classified in the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) as a “trauma and stressor-related disorder” and is the only psychiatric diagnosis (along with acute stress disorder) that depends on a factor outside the person—namely, a traumatic stressor that is outside the range of usual experience involving actual or threatened death or serious injury or assault to self or others (APA, 2013; Mayo Clinic, 2017).


History is replete with accounts of individuals who have experienced or witnessed terrifying events; felt intense fear, helplessness, and horror; and suffered ongoing emotional distress.

  • Following the Civil War (1861–1865), veterans who had developed emotional distress were diagnosed as having “soldier’s heart” (Lamprecht & Sack, 2002).
  • After World War I (1914–1918), veterans with ongoing emotional distress were said to suffer “shell shock”; following World War II (1939–1945), such distress was described as “battle” or “combat” fatigue (Jones, 2005).
  • In 1956, Hans Selye wrote The Stress of Life, in which he described how stressors such as extreme fear disrupt the normal balance of life in a process he called the general adaptation syndrome.
  • Between 1959 and 1973, in the jungles of Vietnam, Laos, and Cambodia, U.S. soldiers fought a terrifying guerilla war in which 58,200 died and thousands suffered injuries. Ongoing psychological distress was common, but veterans had difficulty obtaining disability benefits because there was no accepted psychiatric diagnosis for such emotional and behavioral anguish (Jones, 2005).

In 1989, because of a recognized need, the National Center for Posttraumatic Stress Disorder was established within the U.S. Department of Veterans Affairs. Its mission was and is “to advance the clinical care and social welfare of America’s Veterans through research, education, and training in the science, diagnosis, and treatment of PTSD and stress-related disorders” (NCPTSD, 2011).

Beginning in 2001 in Afghanistan and 2003 in Iraq, military action brought increased evidence of the long-term effects of urban warfare and of other terrifying events upon the human psyche. As a result, PTSD is now the focus of intensive scientific study, including:

  • Research conducted during the six months after the Boston Marathon bombing in 2013 found that children who were at the marathon finish line suffered from posttraumatic stress disorder at a rate six times higher than those who did not attend (Comer et al., 2014).
  • Research reported from 1993 through 2013 found that the incomplete abolition of the cognitive faculties of memory and learning during anesthesia may lead to an awareness episode with severe consequences on psychological health, including PTSD (Aceto & Lai, 2016).
  • Numerous population-based studies demonstrate that patients with PTSD are more likely to develop and die from cardiovascular disease (Arenson & Cohen, 2017).

Posttraumatic stress disorder occurs following exposure to a terrifying, stressful, or frightening event or after prolonged traumatic experience. Types of events that can lead to the development of PTSD include:

  • Interpersonal violence: Childhood physical abuse, witnessing interpersonal violence, physical assault, or being threatened by violence
  • Sexual relationship violence: Rape, childhood sexual abuse, intimate partner violence
  • Interpersonal-network traumatic experiences: Unexpected death of a loved one, life-threatening illness of a child, other traumatic event of a loved one
  • Exposure to organized violence: Being a refuge, kidnapped, or civilian in a war zone
  • Participation in organized violence: Military combat exposure, witnessing death or serious injury, discovering dead bodies, accidentally or purposefully causing death or serious injury to others
  • Other life-threatening traumatic events: Life-threatening motor vehicle accidents, gas explosions, fires, infectious disease epidemics, radiation, mass casualties, or natural disasters

Source: Sareen, 2017.


Prevalence and Vulnerability

In the United States, 7.7 million Americans age 18 and older have PTSD. Lifetime prevalence of PTSD ranges from 6.8% to 12.3% in the general adult population, with women (10.4%) twice as likely as men (5%) to have PTSD at some point in their lives. According to a study of 368 individuals, 65% reported a history of being exposed to potential or actual severe traumatic events, and of these 12% went on to develop PTSD (Sareen, 2017).

Sixty-seven percent of people exposed to mass violence (human-caused tragedies) have been shown to develop PTSD, a higher rate than those exposed to natural disasters or other types of traumatic events (Gradus, 2017).

Vulnerability is influenced both by the characteristics of the individual as well as those of the event. Traumas that are intentional have been found to be more closely associated with PTSD than those that are unintentional or nonassaultive.

The rates of PTSD among men and women are similar following such events as accidents, natural disasters, and the sudden death of a loved one. Men develop PTSD at a higher rate than women following an incidence of rape, even though women experience rape 10 times more often than men. PTSD development, however, is higher in women following events such as molestation and physical assault.

Sexual assault is the most frequent type of traumatic event among women with PTSD. Among women who have a history of PTSD, 32% had been raped and 31% were sexually assaulted but not raped (Sareen, 2017).

Native Americans and Alaska Natives living on tribal lands have higher rates of PTSD, with a lifetime prevalence ranging from 14.2% to 16.1%, attributed to the higher rates of exposure to interpersonal violence among this population. Another reason may be that over many generations these tribes have endured a progression of traumatic events that have had lasting consequences for the members of the community. It is recognized that there is a critical connection between these historically traumatic events and contemporary stressors (Hardy & Brown-Rice, 2016; Bassett et al., 2014; Evens-Campell, 2008).

Among refugees escaping mass conflict, the prevalence of PTSD is as high as 31% and is associated with the higher incidence of torture, the cumulative exposure to trauma, and how recently the exposure occurred (Haagen et al., 2017).

PTSD and Military Personnel

Among veterans of the Iraq and Afghanistan wars, PTSD has been reported at 20%—with a range of 9% shortly after returning from deployment to 31% a year after deployment (Veterans and PTSD, 2015).

The occurrence of PTSD following combat injury has been correlated strongly with the extent of the injury and with the occurrence and severity of a traumatic brain injury. Almost 50% of soldiers with traumatic brain injury meet the criteria for a diagnosis of PTSD (Sareen, 2017).

Among female veterans, the prevalence of PTSD keeps pace with male veterans (20%). However, because only 11% to 17% of female veterans get their care through the VA, where prevalence data is often obtained, as compared to 26% of male veterans, the full effects of PTSD in female veterans is still unknown (NVF, 2015).

Stroke and Cardiac-Induced PTSD

Because of the advancement in medical technology both in the community and in-hospital, more people are living with the memory of life-threatening events. There is growing awareness that these patients are prone to the development of PTSD. Prevalance rates of PTSD vary depending upon the type of events.

  • One in 4 stroke survivors have been shown to develop PTSD, and 1 in 9 stroke survivors experience chronic PTSD more than a year later (Lazarony, 2016).
  • Individuals who experienced myocardial infarction or unstable angina have been found to have a prevalence rate of 12%, and approximately 19% to 38% of those who suffer a cardiac arrest go on to develop significant symptoms of PTSD.
  • Those patients with implantable cardioverter defibrillators experience a 20% prevalence rate of PTSD.
    (Tulloch et al., 2015)

ICU-Induced PTSD

Researchers at Johns Hopkins University have found that nearly 25% of ICU survivors go on to develop PTSD, and a review of the literature found a prevalence of PTSD among patients who had been treated in an ICU to range from 10% to 60%. Neither the severity of the illness nor the length of ICU stay were predictors of PTSD, but factors for development of PTSD included benzodiazepine use, early memories of ICU experiences, and pre-ICU psychopathology (Parker et al., 2015).

PTSD and Suicide

Suicide risk is higher in trauma survivors, and studies show that suicide risk is also higher in persons with PTSD (Hudenko et al., 2017). Among people who have had a diagnosis of PTSD at some point in their lifetime, approximately 27% have also attempted suicide (Tull, 2017).

PTSD in Children and Adolescents

Currently, there have been no epidemiological studies done to determine the prevalence of PTSD among children in the general population. However, research does indicate that children exposed to traumatic events may have a higher prevalence of PTSD than adults in the general population (Gradus, 2017).

In an assessment of adolescents, it has been found that 5% of adolescents have met criteria for PTSD in their lifetime. Prevalence is higher for girls than boys (8.0% vs. 2.3%) and increases with age (Hamblen & Barnett, 2016).


Although PTSD is always triggered by an external event, it may have roots in one’s biology as much as experience. Studies have shown there are biochemical, physiologic, and sociocultural causes as well as occupational factors and personal variables involved in the development of PTSD.

Neurological Basis of Memory and Trauma

When an individual is experiencing a traumatic event, there is a heightened emotional status and an elevated signal for storage of the event in the memory in an interconnected neural network, and a trauma network is established. This trauma network includes the sensory, cognitive, physiological, and emotional experience and also includes the action or response the person made to it (“fight or flight”).

Environmental stimuli (such as a noise or a smell) or an internal stimulus (such as a thought) can activate this trauma network later at any given time. At some point, the activation of only a few elements in the network is enough to activate the whole structure, and the activation of the whole structure is thought to be a flashback, one of the cardinal symptoms of PTSD (Czeh & Fuchs, 2016).


Stress is an essential and normal physiological response to the environment and greatly influences memory. Stress is the number one risk factor in the development of PTSD, and prominent memory disturbances are a central feature of this disorder.

Pathophysiological research to date has focused on areas of the brain associated with processing fear and memory. These areas are the hippocampus, the amygdala, and the medial prefrontal cortex, including the anterior cingulate gyrus (which is a part of the limbic system involved with the processing of emotions and the regulation of behavior as well as regulating autonomic motor function).

Both the hippocampus and amygdala are key elements in human memory. The hippocampus is responsible for the processing and storage of short-term memory, and the amygdala is responsible for activities that include emotion and moods and appears to modulate all reactions to events that are important to survival.

Neurobiological researchers currently are focused on:

  • Structural changes in the brain. The reduction in the size of the hippocampus visible on brain imaging has been found to occur in individuals with chronic or complicated PTSD and is believed to be caused by an overproduction of cortisol.
  • Regulation of the amygdala. The failure of the medial prefrontal-anterior cingulated networks to regulate amygdala activity has been found to result in a hyperactive response to threat. An over-reactive amygdala can tell the person that what is in reality a safe situation is threatening.
  • Hypothalamic-pituitary-adrenal (HPA) axis. The HPA is the major mechanism by which the body responds to stress. The hypothalamus releases corticotrophin-releasing hormone (CRH), which activates the release of adrenocorticotropic hormone (ACTH) from the pituitary gland. This hormone is transported by the bloodstream to the adrenal glands, where it stimulates the production of glucocorticoid hormones. Cortisol acts as a feedback loop to suppress CRH release from the hypothalamus and thus suppress ACTH release from the pituitary. An oversensitive negative-feedback system causes a failure to contain the sympathetic response, thereby strengthening traumatic memories. Those with PTSD have abnormal levels of stress hormone (lower levels of cortisol, higher levels of epinephrine and norepinephrine).
  • Neurochemical pathways. What has not been understood to this point is the neurochemical pathways that lead to impaired hippocampal-dependent memory (BMJ, 2017; Nursey & Phelps, 2016; Matosin & Cruceanu, 2017).
  • Genetics and inflammation. More recently, researchers have implicated immune genes as biomarkers in risk for PTSD. Such studies are addressing the molecular mechanism that could be underlying the immune system tipping toward a dysregulated inflammatory state in PTSD (Wang & Young, 2016).

Risk Factors

Numerous causes beyond the precipitating trauma can increase the risk for development of PTSD.

Pretraumatic Risk Factors

  • An earlier life-threatening event or trauma such as child abuse
  • Childhood emotional problems before age 6 years
  • Having another mental health problem
  • Having a family member with mental health problems
  • Recent loss of a loved one, especially if not expected
  • Recent stressful life changes
  • Choice of occupation (e.g., firefighter, police, EMS, military)
  • Heavy use of alcohol
  • Being female
  • Being poorly educated
  • Lower intelligence
  • Lower socioeconomic status
  • Minority racial/ethnic status
  • Genetic factors (however, no specific genes associated with PTSD risk have as yet been identified)

Peritraumatic Risk Factors

  • Greater the severity of the trauma, greater the risk for PTSD
  • Greater perceived threat to life
  • Feeling helpless
  • Uncontrollability of the event
  • Whether the traumatic event was intentional (disaster or accident) or deliberate (combat, assault, abuse)

Posttraumatic Risk Factors or Recovery Environment

  • Little or no support from family and friends
  • Life stressors following trauma
  • New trauma
  • Resilience
  • Being male
  • Younger age
  • Heavy use of alcohol

(Hamblen, 2017)


Differences in risk factors between males and females are being studied to determine why women have a higher pretraumatic risk and men a have higher posttraumatic risk for developing PTSD. Studies thus far show that:


  • Are more prone to depression, which is known to increase risk
  • Are more likely to experience trauma within established relationships
  • Are more likely to be exposed to chronic trauma (interpersonal violence)
  • Are socialized to feel responsible for being a victim
  • Are socialized to be responsible for others’ well-being
  • Have a higher prevalence of sexual abuse and greater fear of sexual trauma
  • Produce oxytocin, which buffers “fight or flight,” has a calming effect, and leads to “tending and befriending” behaviors in times of stress
  • Are more willing than men to seek help after a traumatic event


  • Produce oxytocin, but testosterone release in response to stress reduces its effects
  • Respond to traumatic events with fight (aggression) and flight (social withdrawal, substance abuse)
  • Experience stigma due to stereotypes that impact help-seeking early in the course of illness

Sources: Vogt, 2017; Sippel et al., 2017; Nickels et al., 2017.


It is important to note that not everyone who experiences a traumatic event goes on to develop PTSD. In fact, most people do not, as resilience factors can help reduce the risk of the disorder (NIMH, 2016).

People respond to trauma in remarkably different ways. When a group of unrelated individuals is exposed to the same traumatic event, one person may develop a full-blown stress disorder lasting for months or years; one may become depressed and suicidal; and another may experience only mild, transient symptoms.

Resilience is thought of as “bouncing back” from harm. It is the process of adapting well in the face of adversity, tragedy, trauma, or other significant threats or stress. Resilience involves behaviors, thoughts, and actions that can be learned and developed.

A combination of factors contributes to resilience, primary of which is having caring and supportive relationships within and outside the family. Other factors include:

  • The capacity to make realistic plans and take steps to carry them out
  • A positive self-image and confidence in strengths and abilities
  • Communication and problem-solving skills
  • A capacity to manage strong feelings and impulses
    (APA, 2017a)


The DSM-5 divides PTSD symptoms into four clusters: intrusion, avoidance, negative alterations in cognition and mood, and alterations in arousal and reactivity (APA, 2013).


Intrusion is a core symptom of PTSD and can take the form of unwanted and obsessive thoughts, feelings, sensory experiences, or any combination of the three relating to the experienced trauma. These can include:

  • Involuntary, recurrent, and intrusive memories
  • Traumatic distressing dreams or nightmares
  • Dissociative reactions (flashbacks) in which the person feels or acts as if the traumatic event(s) were recurring
  • Intense or prolonged distress postexposure to internal or external cues symbolizing the event(s)
  • Marked physiological reactivity postexposure to internal or external cues


Efforts to avoid distressing trauma-related stimuli may persist, including:

  • Trauma-related thoughts or feelings
  • Trauma-related external reminders such as persons, places, activities, situations, or objects

Negative Alterations in Cognitions and Mood

Such alterations in cognitions and mood begin or worsen after the traumatic event, and include:

  • Inability to recall important feature(s) of the event (dissociative amnesia)
  • Persistent and often distorted negative beliefs and expectations about self or others
  • Persistent blaming of self or others for the cause of the traumatic event or the consequences following the event
  • Persistent negative emotions related to the trauma, such as fear, anger, guilt, shame, or horror
  • Greatly reduced interest in normal activities
  • Feeling detached or estranged from others
  • Persistent inability to experience positive emotions

Alterations in Arousal and Reactivity

Alterations in arousal and reactivity begin or worsen after the traumatic event and include:

  • Irritability or aggressive behavior
  • Self-destructive or reckless behavior
  • Hypervigilance
  • Exaggerated startle response
  • Problems concentrating
  • Sleep disturbance

Symptoms in Children and Adolescents

Classic PTSD symptoms apply to both adults and children, and PTSD is diagnosable beginning at 1 year of age. However, young children express symptoms differently. Because of the lack of language development, infants and young children often cannot talk about what happened. Instead, they may:

  • Show fear of strangers or be afraid to leave a parent
  • Develop sleep problems or nightmares
  • Experience thoughts that focus on specific words or symbols that may or may not be directly related to the trauma
  • Demonstrate play behaviors with repeated themes of the trauma, often in an agitated and frightened way
  • Replay the trauma through artwork
  • Be more fussy, irritable, aggressive
  • Be more easily startled, very aware of danger
  • Have frightening dreams unrelated to the traumatic event
  • Have vague physical complaints, such as headaches or stomachaches
  • Lose skills once attained, such as toilet training
  • Forget how or be unable to talk
  • Be unusually clingy with a parent or other adult
  • Revert to earlier habits for comfort, such as thumb sucking
    (McLaughlin, 2017)

Older children ages 12 to 15 may not have visual flashbacks or amnesia for the trauma as adults often do, but they can experience mis-sequencing of the trauma-related events when recalling the memory, and they believe there were warning signs that predicted it. As a result, children often believe that if they are alert enough, they will recognize warning signs and avoid trauma in the future. This is referred to as omen formation.

School-aged children also are reported to exhibit posttraumatic play or reenactment of the trauma in play, drawings, or verbalizations. Posttraumatic play differs from reenactment in that it is a literal representation of the trauma, involves compulsively repeating some aspect of the trauma, and does not relieve the child’s anxiety.

Other symptoms may include:

  • Loss of trust in the parent or caregiver
  • Negative view of the world
  • Difficulty concentrating
  • Loss of appetite
  • Defiance, or intense angry outburst or aggression
  • Loss of interest in things they have always enjoyed
  • Depressed mood changes
  • Body complaints including stomachaches, headaches, aches, and pains
  • Trouble sleeping alone
    (BCCH, 2017)

Adolescents and teens may manifest symptomatology more closely akin to PTSD in adults, with a few differences. Adolescents are more likely to engage in traumatic reenactment in which they incorporate aspects of the trauma into their daily lives, such as carrying a weapon after being exposed to violence. In addition, adolescents are more likely the younger children or adults to exhibit impulsive and aggressive behaviors.

Other symptoms in adolescents and teens may include:

  • Fear of being alone
  • Loss of trust
  • Being very irritable, having angry outbursts
  • Defiance and aggression
  • Repeated thoughts of death, dying, killing self
  • Risky behavior, alcohol and drug use, unprotected sexual behavior
  • Self injury, cutting
  • Loss of appetite
  • Depressed mood changes
  • Loss of interest in activities formerly enjoyed
  • Body complaints
    (Hamblen & Barnett, 2016; BCCH, 2017)

Valerie, Age 12

Valerie is a 12-year-old seventh grader who has been referred by her art teacher to the mental health counselor at her school. The teacher has become more and more concerned because Valerie, a normally very happy and conscientious student, has recently begun missing class and her grades have been declining over the last two or three months. The teacher also noted that Valerie has withdrawn from her many friends and appears sad and distracted when in class.

When working on an art project recently, Valerie became upset and tearful and asked to be excused to see the school nurse because she was feeling ill. After she was excused, the art teacher looked at the work Valerie was creating, a landscape painting done in acrylics, and was shocked to see the figure of a young man lying in the grass, painted with splotches of red as if covered with blood.

When the mental health counselor meets with Valerie, he asks her about any recent events that may have caused her distress. Valerie tells him about an event she and her friends witnessed a couple of months ago. They were in the local park after dark one night, and they saw three young men, one with a gun, beating up another man. She and her friends watched from a distance and ran away when the man holding the gun turned and saw them.

Since then, she has been unable to see her friends because they remind her of the event, and she has been having a very difficult time trying to stop thinking about it. Valerie reports that she has not told her parents about the event because she and her friends were not supposed to be in the park after dark. She says that she is having nightmares, is afraid to fall asleep, and is more and more irritable and aggressive toward her siblings. She says she does not feel safe anymore and is very afraid to go anywhere near the park.

Valerie and the counselor spend some time talking about her feelings and concerns, and following the meeting, the counselor contacts her mother. Following discussion, arrangements are made to refer Valerie for further evaluation for potential PTSD.


The onset and course of PTSD is unpredictable, and the severity and timing of symptoms are different for each individual. Symptoms may appear immediately but generally present themselves within the first three months following exposure to trauma. There may, however, be a delay of months or even years before criteria are met for the establishment of a PTSD diagnosis.

Individuals who have an immediate onset of symptoms have been found to have a better response to treatment, less severe symptoms, fewer associated symptoms or complaints, and symptom resolution within six months.

Approximately 25% experience a delayed onset after six months or more. These individuals go on to develop associated symptoms and conditions, and PTSD is more likely to become chronic. Delayed onset has a worse prognosis for recovery. One third of patients with delayed onset recover after one year, but one third remain symptomatic 10 years following exposure (APA, 2017b).


Alex, Age 29

Alex Moore, age 29, was brought to the emergency department (ED) by his sister. She awoke in the night and found him writing a suicide note at the kitchen table. The smell of alcohol was on his breath, and there were bottles of both pain and sleeping pills beside him. Five weeks earlier, Alex had left his wife in Texas and driven to his sister’s home in California. Three weeks after that he got drunk, wrecked his truck, and became dependent on his sister for transportation. When she confronted him at the kitchen table, he said, “I’m no damn good to anyone. You’ll all be better off without me.” After much pleading, his sister talked Alex into going with her to the local hospital’s ED.

In the ED Alex’s manner was subdued but somewhat hostile, especially when the staff decided to admit him to the hospital as a “danger to self.” His sister gave further history: For several years Alex had been a firefighter. He and his best friend and fellow firefighter were fighting a fire at a factory when there was an explosion. He saw his friend engulfed in flames and could not get to him. His friend died, but Alex survived and blamed himself for not saving him. Six months later, Alex walked off the job and hasn’t gone back since then. He has not been able to “settle down” or keep a job and has had frequent outbursts of anger, difficulties in his marriage, trouble sleeping, nightmares that he refuses to discuss, difficulty concentrating, and chronic fatigue.

In the hospital Alex was passive, withdrawn, and irritable. He sat stone-faced in group meetings, refusing to participate. He was easily startled by sounds, avoided news programs and movies containing violence, and wandered around the ward checking doors and windows.


Persons with PTSD very commonly have other mental health problems or disorders. Having a mental disorder prior to exposure to trauma appears to increase the chance of the development of PTSD; but having PTSD also seems to increase the risk for the development of other mental health disorders (NCPTSD, 2017a).

Data from the National Comorbidity Survey suggests that 16% of patients with PTSD have one coexisting psychiatric disorder, 17% have two disorders, and 50% have three or more (Sareen, 2017).

Psychiatric Disorders

Depression often occurs after exposure to trauma. PTSD and depression are very often co-occurring conditions. National surveys show that depression is nearly 3 to 5 times more likely in those with PTSD than those without. Many symptoms of PTSD overlap with those of depression. The symptoms of both depression as well as PTSD can make it difficult to function and may interfere with the person seeking treatment (NCPTSD, 2015a).

Patients with PTSD have been found to have higher rates (24%) of co-occurring borderline personality disorder (BPD) and antisocial personality disorder compared with the general population. Those with comorbid PTSD and BPD have an increased risk of suicide attempts and high levels of traumatic events in childhood (Sareen, 2017).

Substance Use Disorder (SUD)

PTSD and substance use disorder often occur together. National studies have found that 46% of individuals with lifetime PTSD (28% of women and 52% of men) also met criteria for SUD. Women with PTSD are 2.5 times more likely to meet criteria for alcohol abuse or dependence and 4.5 times more likely to meet criteria for drug abuse or dependence than women without PTSD. Men were 1 and 3 times more likely, respectively. PTSD and SUD are both associated with functional impairment, and individuals who have both disorders have poorer treatment outcomes (NCPTSD, 2017a).

Chronic Pain

The prevalence of PTSD is greatly elevated in individuals with chronic pain—35% among chronic pain patients compared to 3.5% in the general population. Studies show that 51% of patients with chronic low back pain had significant PTSD symptoms, and researchers have found that 50% of patients who experience chronic pain following a motor vehicle accident go on to develop PTSD. Adult survivors of physical, psychological, or sexual abuse tend to have higher risk for development of certain types of chronic pain in their lives, the most common of which involve fibromyalgia, interstitial cystitis, and nonremitting whiplash syndromes (DeCarvalho, 2016).

Neurocognitive Disorders (NCD)

The pathways through which PTSD and neurocognitive disorders, including traumatic brain injury (TBI), affect each other are unclear. Evidence so far suggests that PTSD symptoms may be more severe in persons with dementia, general cognitive impairment, and mild TBI compared to persons without those conditions. Most research on TBI and PTSD suggest that experiencing mild TBI places one at greater risk for PTSD, and those who sustained a mild TBI were almost twice as likely to have PTSD than those who have not (Yoder & Normal, 2016).

Physical Health

Much research finds that PTSD may lead to poor health outcomes. Those with PTSD symptoms are more likely to have a greater number of physical health problems than those who do not. Current thinking is that trauma causes neurochemical changes in the brain that may affect health biologically as well as psychologically and behaviorally. Neurochemical changes may cause a vulnerability to cardiovascular disease, for example, as well as abnormalities in thyroid and other hormone factors. PTSD is also associated with increased susceptibility to infections and immunological disorders as well as gastrointestinal and musculoskeletal disorders (Jankowski, 2016).


A serious consequence of PTSD can be suicide. There is a correlation between many types of trauma and suicidal behaviors. Traumatic events such as childhood abuse may increase an individual’s risk for suicide, as may having a history of military sexual trauma. Studies indicate that PTSD is significantly associated with suicidal ideation and attempts after controlling for comorbid disorders.

There is considerable debate as to the reason for the heightened risk of suicide in trauma survivors. Some suggest that the risk is higher among those with symptoms of PTSD, and others claim the risk is higher in those individuals because of related psychiatric conditions. A national data analysis, however, showed that PTSD alone out of six anxiety diagnoses was significantly associated with suicidal ideation or attempts (Hudenko et al., 2017).

Comorbidities in Children and Adolescents

In the United States, 35% of children with PTSD also meet criteria for another lifetime psychiatric disorder. Children with PTSD often present with psychiatric diagnoses including anxiety disorders, depression, externalizing behavior problems, as well as substance use disorders among adolescents (McLaughlin, 2016).


Living and working with survivors of trauma suffering with PTSD symptoms can have profound effects on those closest to them and those who are caring for them.

Impact on Intimate Partners

There is a strong association between PTSD and intimate relationship problems: a higher rate of divorce, greater impairment in emotional expressiveness, more verbal and physical aggression against partners and children, and more sexual dysfunction. Partners of individuals with PTSD also report a greater incidence of individual difficulties such as depression, anxiety, and caregiver burden (Pukay-Martin et al., 2016).

Impact on Family Members

PTSD can cause major difficulties within the family. PTSD symptoms make it difficult for family members to cope with and get along with the sufferer. Reactions of many family members can include:

  • Sympathy. Family members may feel sorry for the person, which can be helpful initially. It can have a negative effect, however, when it leads to low expectations of the sufferer, eroding his or her confidence in the ability to recover from the trauma.
  • Depression. Changes in how the family functions because of the effects of PTSD symptoms on the sufferer can lead to feelings of pain or loss, increasing the risk for the development of depression. If PTSD lasts for a long time, family members may lose hope that the family will ever be “back to normal.”
  • Fear and worry. When a PTSD sufferer is worried, fearful, and preoccupied with trying to feel safe, it can make others in the family feel unsafe also. Fear is also experienced when the PTSD sufferer is angry or aggressive.
  • Avoidance. Family members may avoid talking about the traumatic event and avoid the same things the PTSD sufferer does because they do not want to cause further pain or are fearful of the person’s reactions.
  • Guilt and shame. A family member may feel guilt or shame for many reasons, but especially if he or she feels responsible in same way for the trauma, for example, being unable to protect the person from the trauma.
  • Anger. Family members may feel angry about the trauma, its effect on their lives, and with whomever is believed to be responsible for the event. They also may feel anger toward the PTSD sufferer who cannot “get beyond the trauma and move forward in life.” Family members may also feel angry and irritable in response to the anger and irritability the trauma survivor directs toward them.
  • Negative feelings. Family members may begin to feel the person is no longer the same one they knew before the trauma. They may feel negatively about behavior exhibited by the sufferer both during and following the traumatic event. Sometimes family members have these negative feelings even when they know that their assessment of the situation is unfair.
  • Drug and alcohol use. Family members may attempt to escape from bad feelings by using drugs or alcohol. A child or a spouse might spend time drinking with friends to avoid having to go home. In other situations, spouses may abuse drugs or alcohol to keep the trauma survivor company when the person is drinking or using drugs to avoid trauma-related feelings.
  • Sleep problems. When the person with PTSD cannot sleep, it may be difficult for family members to sleep as well. Sleep problems may also be due to depression.
  • Health problems. Bad habits (e.g., drinking, smoking, not exercising) may worsen among family members, and with extended stress, they may become more likely to develop stomach or bowel problems, headaches, muscle pain, and other health problems.
    (Carlson & Ruzek, 2016)

Impact on Healthcare Professionals

One of the special characteristics of healthcare professionals is the ability to share the emotions of someone who is suffering. This is referred to as empathy and can be extremely beneficial to a patient’s well-being. A step beyond empathy is compassion. Compassion is more engaged than simple empathy and is related to an active desire to alleviate another’s pain.

Research has shown that health professionals working with trauma patients may experience PTSD symptoms as an indirect response to their patients’ suffering. This has been referred to as compassion fatigue or vicarious traumatization, which describes the profound emotional and physical erosion that occurs when persons in the helping professions are unable to replenish and rejuvenate.

Compassion fatigue and vicarious traumatization develop over time, sometimes taking weeks or even years to emerge. It is a low-level, chronic clouding of caring and concern for others. An erosion of the ability to feel and care for others occurs through the overuse of the skills of compassion. Emotional blunting may occur, and the individual may react to situations differentially than would normally be expected (Oshberg, 2017).


Primary support persons are family members or close friends who play the roles of advocate, confidant, and “cheerleader.” Healthcare workers are often involved with primary support persons, assisting them to help with treatment and cope with the patient’s symptoms as well as to take care of themselves. It is beneficial if support persons are assisted to:

  • Become educated about PTSD. The more support persons know about the symptoms, effects, and the treatment options for PTSD, the better they can understand what the patient is going through and keep things in perspective. When support persons are involved in the treatment process, patients experience a reduction in symptoms and family environment is improved.
  • Avoid pressure but be willing to listen. Do not try to force the person with PTSD to talk. Support persons should understand that patients may have difficulty talking about their traumatic experiences, and in some cases, talking can make things worse. They can be encouraged to be ready to listen when the patient is ready to speak.
  • Be patient. It is important for support persons to understand that the process of recovery takes time and that there are often setbacks; the important thing is to remain positive and be patient.
  • Recognize that withdrawal is part of the disorder. Often the patient may resist help.  When this occurs, support persons should allow “breathing room” and let the patient know they are available when he/she is ready to accept help.
  • Offer to attend medical appointments. When a support person attends appointments along with the patient, it can increase understanding and assistance with treatment.
  • Encourage participation. Even though it may be difficult for the patient, it is important that support persons encourage him or her to return to a normal routine that includes socialization and celebrating with friends and family.
  • Encourage contact with family and friends. A support system can help the person get through difficult changes and stressful times.
  • Encourage physical activity. Exercise provides both physical and psychological benefits. It is important for health and helps clear the mind.
  • Make personal health a priority. By eating a healthy diet, getting enough exercise and rest, taking time to be alone or with others involved in activities that are rejuvenating, it is easier for support persons to maintain a positive attitude.
  • Seek help if needed. Support persons who are having difficulty coping can seek help from family, support groups, or healthcare providers, who may refer them to a counselor or therapist.
  • Stay safe. Recognizing that safety may become an issue, a plan should be in place for the support person and other vulnerable members of the family in the event the patient becomes violent or abusive.

Source: NCPTSD, 2015b.


There is a wide range of professionals who interact with people at risk for developing PTSD and those who have PTSD whether or not they have already been diagnosed. Healthcare professionals are critical in facilitating the recovery process if they routinely incorporate the following into practice:

  • Being alert to recognize and identify PTSD symptoms
  • Utilizing screening tools for PTSD as part of a general health assessment (e.g., Primary Care PTSD Screen, Trauma Screening Questionnaire, SPAN)
  • Exploring the possibility of PTSD as an underlying problem when appropriate
  • Being familiar with local referral options for further assessment and directing patients to appropriate referrals when necessary
  • Offering support to patients and families

Clinical Interview

Individuals who screen positive for PTSD are referred for additional evaluation, which is typically a face-to-face interview by a health professional trained in diagnosing psychiatric disorders. A face-to-face interview is the optimal method of assessment to determine a PTSD diagnosis. Clinical interviews can be structured, semi-structured, or unstructured.

  • Structured interviews require adherence to a very exacting set of rules, with no variation from the protocol. The interviewer may also be required to be consistent in behavior, and reactions to the patient’s responses are to be kept to a minimum or avoided entirely.
  • Semi-structured interviews are more relaxed. The interviewer is expected to cover every question in the protocol, but there is room to explore participant responses. The interviewer is allowed to be more friendly and sociable. This type of interview is useful when discussing a topic that is very personal to the patient. 
  • Unstructured interviews are the most relaxed. The interviewer requires only a checklist of topics to be covered. There is no order and no script. The interaction between the patient and the interviewer is more like a conversation than an interview.

Formal Assessment Tools

Structured and semi-structured interviews are most often conducted utilizing a formal assessment tool.


The following are used in the assessment of PTSD in adults:

  • Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). This is the “gold standard” in PTSD assessment. It is a 30-item structured interview designed to be administered by clinicians and appropriately trained paraprofessionals. The interview is used to make a current or lifetime diagnosis of PTSD and to assess PTSD symptoms over the previous week. The full interview takes 45 to 60 minutes to administer (Sareen, 2017).
  • PTSD Checklist for DSM-5 (PCL-5). This is a 20-item self-report measure that assesses the 20 DSM-5 symptoms of PTSD. It is used to monitor symptom change during and after treatment, screen for PTSD, and make a provisional PTSD diagnosis. This tool takes 5 to 10 minutes to complete and can be completed by patients in a waiting room (Sareen, 2017).
  • Life Events Checklist for DSM-5 (LEC-5). This is a self-report measure that screens for potentially traumatic events in a patient’s lifetime. It assesses exposure to 16 events known to have the potential to result in PTSD and includes one additional item to assess for any other extraordinarily stressful event not captured in the first 16 items. There are three formats for LEC-5, including the standard self-report that establishes whether an event has occurred, the extended self-report that establishes the worse event if more than one, and the interview to establish if Criterion A stressor has been met.
    (NCPTSD, 2017b)


For children and adolescents, the following tools are helpful when assessing for PTSD:

  • UCLA PTSD Reaction Index for Children and Adolescents (PTSD-RI) is a widely used instrument that can be administered to children and adolescents, as well as to parents, and can be completed by self-report or by interview. It contains 125 items and provides a count of the number of distinct types of trauma a child may have experienced. It is used to diagnose PTSD and is also used to provide a continuous severity score for PTSD symptoms.
  • Clinical Administered PTSD Scale for Children and Adolescents (CAPS-CA5) is a 30-item structured interview for assessing trauma exposure and PTSD symptoms in children older than 7 years. It is used to make a diagnosis of PTSD.
    (McLaughlin, 2016)


The recommendations for assessment of an older adult include a full Mental Status Examination, including a cognitive screening. If dementia is suspected, the patient should be referred for a comprehensive diagnostic evaluation. If delirium or possible medication interaction is suspected, the patient should be referred for medical evaluation.

The same “gold standard” assessment tool, CAPS-5, is recommended for the older adult. When interviewing older adults, it should be understood that older patients may talk about problems or respond differently to questions than younger people. They may be less likely to identify problems from a psychological point of view and be more likely to report physical concerns or pain, sleep difficulties, cognitive problems, or gastrointestinal issues.

Veterans, for example, may attribute problems to more current issues and the aging process, and may not relate symptoms that occurred long ago. PTSD stress symptoms were often overlooked in older adults because PTSD is a fairly recent identified disorder, and older adults who were exposed to traumatic events earlier in life and had symptoms following them were not identified.

In addition, the older adult is likely to have more medical problems, co-occurring psychiatric problems, and cognitive problems that can complicate the assessment and treatment of PTSD. Suicide assessment is particularly important in older patients (Hermann, 2017; Kaiser et al., 2017).

Physical Examination

Any patient presenting with symptoms of PTSD should have a complete history and physical examination to rule out any other causes for symptomatology, such as endocrine, cardiovascular, and neurological disorders. A review of systems and social history should also address the use of over-the-counter medications and mood-altering substances such as prescribed medications, alcohol, marijuana, or other substances of abuse.


Medical Diagnosis

A medical diagnosis is the naming of a disorder based on an assessment of physical signs and symptoms, medical history, and results of diagnostic tests and procedures. The DSM-5 establishes the criteria required in order to make the medical diagnosis of PTSD, as described in the table below.

Criterion Requirement
Source: APA, 2013.
A. Stressor Must be exposed to death, threatened death, actual or threatened serious injury, or actual or threatened sexual violence. Must have one of the following:
  • Direct exposure
  • Witnessing, in person
  • Indirect exposure, by learning that someone close was exposed to trauma, and if involved, actual or threatened death must be violent or accidental
  • Repeated or extreme indirect exposure to details of traumatic event(s) such as experienced in the course of occupation (e.g., EMS personnel, police, firefighters); does not include indirect nonprofessional exposure through electronic media, television, movies, or pictures
B. Intrusion Must have one of the symptoms in this symptom cluster (see “Symptoms” earlier in this course)
C. Avoidance Must have one of the symptoms in this symptom cluster (see “Symptoms” earlier in this course)
D. Negative alterations in cognitions and mood that worsened after the traumatic event Must have two of the symptoms in this cluster (see “Symptoms” earlier in this course)
E. Alterations in arousal and reactivity that began or worsened after the traumatic event Must have two of the symptoms in this cluster (see “Symptoms” earlier in this course)
F. Duration Symptoms having persisted for more than one month
G. Functional Must be significant symptom-related distress or functional impairment in activities of daily living such as socialization and occupation
H. Exclusion Disturbance not due to medication, substance use, or other illness
Specify whether the person experiences dissociative symptoms
  • Depersonalization: Recurrent experiences of feeling detached from one’s mental processes or body
  • Derealization: Persistent or recurrent experiences of unreality of surroundings
Specify if with delayed expression Diagnostic criteria not met until at least 6 months after the event

Alex  (continued)

The mental health team evaluated Alex. His physical examination was within normal limits, and a structured interview was conducted using the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5).

An assessment for PTSD diagnostic criteria revealed that Alex was directly exposed to a stressor when he was involved in the fire and explosion that took the life of his firefighting partner and friend. He was found to have:

  • One intrusive symptom (nightmares that he refused to discuss)
  • One avoidance symptom (not watching news programs and violent movies)
  • Three negative alterations in cognitions and mood that have worsened after the traumatic event (increasing negative thoughts about himself and his self-worth, passivity and withdrawal, and refusing to participate in group meetings)
  • More than two symptoms of alteration in arousal and reactivity (contemplating self-destruction, irritability and outbursts of anger, trouble sleeping, inability to concentrate, startles easily, hypervigilance in checking doors and windows)
  • Duration of symptoms persisting for longer than one month

After review of his history it was determined that Alex did not meet the criteria for PTSD until six months after exposure, resulting in the specifier delayed expression. Alex also met the criteria for functional difficulties, as he is unable to “settle down” or keep a job and has relationship problems.

A medical diagnosis of “posttraumatic stress disorder with delayed expression” was given to Alex after determining that his symptoms met the criteria as set forth in DSM-5.

Nursing Diagnosis

NANDA International (2014) defines a nursing diagnosis as “a clinical judgment about individual, family, or community responses to actual or potential health problems or life processes which provide the basis for selection of nursing interventions to achieve outcomes for which the nurse has accountability.”

Nursing diagnoses that are appropriate to the patient suffering from PTSD include, but are not limited to:

  • Hopelessness/powerlessness
  • Ineffective coping
  • Sleep pattern disturbance
  • Dysfunctional grieving
  • Impaired social interaction
  • Ineffective relationships
  • Impaired individual resilience
  • Risk for suicide and/or self-destructive behavior

Alex  (continued)

On admission to the hospital, a nursing assessment was completed, which included information obtained by interviewing both Alex and his sister, by observations of his behaviors, and by consultation with other members of the team. A nursing care plan was developed for Alex, including the following nursing diagnoses:

  • Risk for suicide related to his feelings of helplessness, hopelessness, and worthlessness, as evidenced by his written suicide note and verbal statements to his sister about her being better off without him
  • Ineffective coping related to PTSD, as evidenced by his inability to keep a job, abruptly leaving his wife, drinking, wrecking his vehicle, and dependence on his sister
  • Sleep pattern disturbance related to his recurring and distressing dreams of fire and explosion as evidenced by verbal statements about having nightmares he refuses to discuss, irritability, and chronic fatigue
  • Dysfunctional grieving related to the death of his friend in a traumatic event as evidenced by quitting his job and his inability to resume normal activities and responsibilities beyond six months of bereavement
  • Ineffective relationships related to cognitive and mood alterations as evidenced by irritability, outbursts of anger, marital problems, and leaving his wife



Planning care involves establishing client-centered goals and expected outcomes, setting priorities, and choosing interventions according to the urgency of each problem. Urgency is measured by client safety, client desires, and nature of the treatment.

Goals and Outcomes

The following are the optimal goals and outcomes for a patient diagnosed with PTSD. The patient will:

  • Maintain safety of self and others
  • Demonstrate control
  • Distinguish between the present and memories
  • Recognize triggers
  • Receive treatment for comorbid conditions, such as alcohol/drug addiction, depression, anxiety disorders, and panic attacks
  • Recognize ineffective coping strategies and correlate to negative outcomes
  • Attend support group meetings
  • Expand social support network
  • Have increased restful sleep periods
  • Have fewer nightmares and flashbacks
  • Express decreased irritability
  • Report feeling control for factors contributing to fear
  • Demonstrate effective anxiety-reducing techniques, either cognitive or behavioral
    (Varcarolis, 2015)

Alex  (continued)

In planning for Alex’s treatment, the most urgent problem is his risk for suicide, followed by a disturbed sleep pattern that impairs thinking. His dysfunctional grieving and ineffective coping should be addressed as he works through and resolves the distressing feelings and memories of the explosion, fire, and death of his friend.

The goals and outcomes for each of Alex’s nursing diagnoses are as follows:

  • Risk for suicide: Alex will refrain from attempting suicide.
  • Ineffective coping: Alex will begin to identify available resources and support systems, describe and initiate alternative coping strategies, and describe positive results from new behaviors.
  • Disturbed sleep pattern: Alex will sleep at least seven hours per night without nightmares.
  • Dysfunctional grieving: Alex will be able to talk about his lost friend in a therapy group.
  • Ineffective relationships: Alex will exhibit appropriate affect and decreased lability.



Interventions for PTSD are generally divided into psychotherapy and pharmacology, with psychotherapy being the primary choice. There are a number of treatment modalities. Some patients respond well to one treatment modality, while others may require a combination of modalities. The goal for patients with PTSD is to regain a sense of control over life.


The most effective types of psychotherapy for treatment of PTSD are various forms of trauma-focused cognitive-behavioral therapy, which most often include elements of cognitive therapy, exposure, and coping skills training.


Cognitive approaches assist patients to correct false perceptions. They are based on the theory that the meanings we impose on events contribute to our emotional states. Therefore, changing how we think about them can reduce PTSD symptoms and promote a sense of well-being.

Cognitive processing therapy (CPT) is one of the most widely researched cognitive approaches, with a primary focus on challenging and modifying maladaptive beliefs related to a trauma. CPT has four main elements and includes a written exposure component:

  • Education about PTSD symptoms and how treatment can help
  • Developing awareness of thoughts and feelings
  • Learning new skills for challenging thoughts and feelings (cognitive restructuring)
  • Learning and developing an understanding about the common changes in beliefs that occur after going through trauma
    (Hamblen et al., 2017)

This form of therapy requires 12 regular sessions of 60 to 90 minutes each with a therapist as well as completing practice assignments at home outside of therapy to help improve skills (NCPTSD, 2017c). Assignments often include hand writing impact statements that address topics such as why the traumatic event occurred and what it means to the patient.

Couples therapy is a conjoint therapy for individuals with PTSD and their partners that has components of both cognitive-behavioral therapy and couples therapy. This intervention, provided in 15 sessions, has been shown to greatly reduce PTSD symptom severity and improve intimate relationship satisfaction (Rothbaum, 2017).


Exposure-based treatments involve having patients repeatedly re-experience the traumatic event. They are intended to help patients face and gain control of overwhelming fear and distress following the traumatic experience.

Prolonged exposure (PE) therapy usually incorporates the patient’s recall of the traumatic event and confrontation with real-life, safe situations that remind the person of the event. PE treatment is given in 90-minute sessions over a 9- to 12-week once- or twice-weekly course. It can be shorter or longer depending upon the person’s needs and response (Rothbaum, 2017).

In some cases, trauma memories or reminders can be confronted all at once, which is referred to as flooding. In other cases, it is preferable to gradually build up tolerance, which is referred to as desensitization. However, prior to exposure, the patient first must learn accompanying coping techniques such as relaxation, mindfulness, or imagery exercises. PE consists of four main elements:

  • Education about treatment symptoms to assist the person to understand the goals of treatment
  • Breathing retraining to aid in relaxation and help in the short-term management of distress
  • In vivo exposure to real-world situations that are safe but have been avoided due to their relationship to the trauma, which over time lessens trauma-related stress
  • Imaginal exposure, involving the repetitive talking through of the trauma, revisiting it over and over aloud and in detail. The narrative is recorded and the patient listens to it between sessions to maximize its therapeutic effect. Talking through the trauma helps gain control of thoughts and emotions about the trauma, make sense of it, and have fewer negative thoughts about it.
    (Rothbaum, 2017; Hamblen, 2017)

Following the exposure part of the session, the patient’s response to the exposure is discussed and maladaptive thoughts are challenged, such as beliefs related to guilt, blame, and responsibility. Homework exercises are often included. This may involve a tape recording made during a session of the patient describing the event. In between sessions, the patient practices exposure at home by listening to the tape and further processing the traumatic material.

A more recently developed method for providing PE is via virtual reality. This form of therapy uses a head-mounted computer display to present the patient with visual, auditory, tactile, and other sensory material that stimulate traumatic memories and affective response. It currently is used to treat veterans exposed to combat, survivors of catastrophic disasters, and in the aftermath of serious motor vehicle accidents (Rothbaum, 2017).


Individual TF-CBT is cognitive-behavioral therapy for children and adolescents with PTSD. It is a parallel child and parent (or primary caregiver) treatment method that incorporates cognitive-behavioral, developmental, neurobiological, attachment, family, and empowerment beliefs. The goals of therapy are to assist children and parents in learning resiliency and new coping skills, to master learned and over-generalized avoidance of feared trauma memories, to make more adaptive meaning of the trauma, and to resume developmental paths (Cohen, 2017).

TF-CBT involves multiple components and phases. During each treatment session, therapy is provided in individual but parallel sessions to the child and the parent, followed by conjoint child-parent sessions. It consists of three phases:

  1. Stabilization phase, which includes psycho-education, parenting skills, relaxation skills, affect modulation skills, and cognitive processing skills
  2. Trauma narration and processing phase
  3. Integration and consolidation phase, which includes in vivo mastery and enhancing safety
    (Cohen, 2017)

Combined parent-child (CPC-CBT) is similar to TF-CBT but is for treatment that includes parents who perpetrated physical abuse. In addition to components of TF-CBT, CPC-CBT includes:

  • A strong focus on developing noncoercive parenting skills
  • Joint parent-child meetings during every session
  • Abuse clarification in which the abusive parent takes full responsibility for the past abuse, alleviates the child of any blame, and addresses other maladaptive cognitions of the child related to abuse
    (Cohen, 2017)


EMDR is another form of cognitive-behavioral therapy that can help change how a person reacts to memories of a traumatic event. It is a fairly new and still-debated form of therapy, and the theories behind it continue to be developed. No one yet knows how this process works, but the mechanisms of EMDR are likely similar to that of other trauma-focused exposure and cognitive therapies. Hypotheses put forth for research are that EMDR works by:

  • Recalling aversive memories in a safe environment, and eye movements do not contribute anything
  • Stimulating interhemispheric communication
  • Taxing working memory during recall
    (Hout & Engelhard, 2012)

EMDR is an individual therapy that involves a course of 4 to 12 sessions, 90 minutes each, focusing on hand movements or tapping while talking about the traumatic event(s). The idea is that rapid eye movements make it easier for the brain to work through traumatic memories. EMDR has four main parts:

  1. Identification of a target memory, image, and belief about the trauma
  2. Desensitization and reprocessing by focusing on mental images while doing guided eye movements taught by the therapist
  3. Installing positive thoughts and images by focusing on a new and positive thought while doing guided eye movements until it replaces the negative thoughts or images
  4. Body scan, focusing on tension or unusual sensation in the body to identify additional issues that need to be addressed in later sessions
    (Hamblen, 2017)


Play therapy is most commonly used with children ages 6 years and younger. It is a cognitive-behavioral therapy technique in which a child’s natural ways of expression (namely, play) are used as a therapeutic method to assist the child to cope with emotional stress or trauma. Sessions usually last about 45 minutes a week for several months (Scheeringa, 2016).

Play therapy for children is effective because feelings are often inaccessible at a verbal level. Instead of verbalizing thoughts and feelings that may be too threatening for a child to express directly, they can be safely projected through self-chosen toys (Hamblen & Barnett, 2017).


Alex  (continued)

Several times during his hospitalization, Alex met with a social worker, who provided education about the PTSD symptoms he was experiencing and explained how treatment could help him restore control over his life. During his sessions with the social worker, he began to develop an awareness of thoughts and feelings that he had not previously understood were related to his trauma.

The multidisciplinary team’s plan of care involved Alex in cognitive-behavioral therapy. Two forms of therapy were felt to be good choices for Alex—Cognitive Processing Therapy and Prolonged Exposure therapy, which are two of the most common CBT methods used to treat PTSD. A psychologist met with Alex and discussed the theory behind Prolonged Exposure therapy to help him understand why he would be asked to do something as scary as reliving his trauma. He was told he would be talking about and reacting to the memories of his traumatic experience, but in the absence of any danger.

During the next session, Alex struggled at first, but with the psychologist’s promptings and urgings began talking about the fire and explosion and how his best friend, Loren, had been killed. He remembered his frantic efforts to try to reach his friend through the flames and smoke. He remembered screaming Loren’s name over and over as he watched his friend go up in flames. Again he felt the fear and frustration of being trapped and helpless as he tried to fight his own way out of the blaze.

During the telling of the event, Alex experienced intense distress and fear and responded physiologically as if he were actually living through the trauma again. He cried softly as he described the death of his friend and repeatedly said, “I’m sorry, I’m so sorry, Loren! I should have saved you. I wish it had been me.” During this session the psychologist recorded his description of the trauma and emotional response. Alex was instructed to listen to this recording sometime during the day and told that they would repeat the session again the following morning.

Alex also began attending group sessions with an occupational therapist. Here he learned about the struggles other patients were having trying to move forward to assume normal activities of daily living and responsibilities. He began opening up and talking more freely. The occupational therapist made an appointment with Alex to complete an assessment of the effects PTSD has had on his ability to work.

With continued treatment, Alex gradually experienced less and less fear, anger, and guilt. He was able to remember his experience without reacting to it negatively and began the slow process of incorporating the event into his other lifetime memories.

Alternative and Complementary Medicine (CAM) Treatments

The use of CAM is widespread for treatment and management of mental health problems, including PTSD. Alternative and complementary medicine refers to treatments not considered standard in current practice. Alternative treatments are those used instead of conventional practices. Complementary treatments refer to the use of these techniques in combination with conventional practices.

Based on currently available evidence, there is no support for the use of CAM interventions as an alternative to currently empirically established approaches for PTSD or as first-line interventions. CAM may be best utilized as an adjunct to other PTSD treatments or as a gateway to additional services for individuals who refuse other approaches.

The Veterans Administration is currently conducting studies in the following:

  • Acupuncture, which appears to have benefit but needs to be evaluated relative to sham acupuncture in order to control for the nonspecific benefits of treatment
  • Mindfulness-based meditation, which appears to have modest benefit
  • Relaxation, which appears to have modest benefit
  • Yoga
  • CAM mind-body practices such as Emotional Freedom Techniques and adjunctive healing touch and guided imagery
    (Strauss et al., 2017)

Occupational Therapy

PTSD can be debilitating, with negative impacts in many areas of a person’s life, making it difficult to carry out the normal activities of daily living. Broad areas affected can include health and safety, money management, self-care, transportation, work, relationship duties, and community participation. PTSD also affects a person’s executive planning abilities such as time management and concentration or paying attention.

Occupational therapists work with PTSD patients of all ages and in all phases of recovery. Following a comprehensive and collaborative evaluation to identify the individual’s strengths and barriers to occupational performance and their causes, OTs provide individual and group therapy sessions that are often done in collaboration with other professionals. Occupational therapy interventions include, but are not limited to:

  • Providing individual and/or group sessions that focus on:
    • Trauma triggers and warning signs
    • Developmental issues related to early childhood trauma
    • Symptom stabilization
    • New coping, health, and wellness strategies such as stress management, relaxation techniques, and sensory processing-related techniques
  • Training clients, caregivers, and interdisciplinary staff in:
    • Adaptive or modified self- and home care, work, or school-based strategies to avoid inadvertent triggering of hypersensitivity patterns, dissociation, flooding, or flashbacks
  • Assisting patients to increase participation in meaningful roles and activities, such as:
    • Creating and using a daily schedule to identify triggers and helpful strategies
    • Identifying and obtaining the type and amount of supports necessary for successful participation
    • Creating and using a sensory diet (a plan of specific activities and experiences used to help balance the nervous system and sensory processing)
    • Implementing exposure techniques
  • Assisting patients and caregivers in determining needs and resources for home modification for those with physical barriers to participation
  • Promoting veterans’ awareness of the impact of wartime driving experiences on PTSD and assisting them in addressing reactions to civilian driving situations
    (AOTA, 2015)


Mickey, an Army veteran, returned home from Iraq, where he drove trucks in combat zones. He was diagnosed with PTSD as a result of this combat experience. Since his return, he has been involved in two minor automobile accidents and received a citation for “inattentive” driving when he was straddling two lanes on the highway.

His mental health therapist was aware that many returning combat veterans have difficulty returning to civilian driving, and their behaviors often were viewed as “road rage” or thrill-seeking. Increasingly, however, these driving behaviors have been identified as symptoms of either a traumatic brain injury or PTSD. For this reason, the therapist suggested to Mickey that he be referred to the North Central Rehabilitation Center for assessment and assistance with driving in a civilian setting.

Carlos, an occupational therapist who is also a certified driving rehabilitation specialist, received the referral and met Mickey for the first time a few days later. At this initial meeting, Mickey learned that the goal of the following sessions would be to conduct a routine assessment and a comprehensive driving evaluation, which was expected to take approximately three hours to complete.

The first part of the evaluation was done in the office. During the initial session, Carlos conducted an examination of Mickey’s physical, visual, and mental abilities required for safe driving, including his reaction time, basic visual acuity, and decision-making.

At the following session, Carlos introduced Mickey to the driving simulator, a technology that provides the illusion of driving an actual vehicle. PTSD response triggers were programmed into two driving scenarios designed to elicit a reaction from the driver. In this instance, nine triggers were included in a simulated rural/suburban drive and ten triggers included in a city/highway drive. The triggers were combat-related and included disabled vehicles, trash at the side of the road, dead animals, unexpected maneuvers made by other drivers, loud helicopter sounds, and engines backfiring.

In the following session during the simulated driving experience, Carlos recorded the number and types of errors Mickey made as well as the verbal responses he made in reaction to the triggers. Mickey’s most common errors were in lane maintenance and vehicle positioning. Following the session, Carlos and Mickey developed a plan of intervention strategies to help overcome Mickey’s combat mindset and improve the skills that are demanded by civilian driving.

Physical Therapy

Physical therapists are not involved in the primary treatment of PTSD but may work with those patients who have experienced an injury sustained during a trauma event that requires physical therapy interventions. Additionally, those with PTSD often experience chronic pain as a result of the complexity of the disorder, in which case the role of the physical therapist in PTSD management is one of mitigating chronic pain.

Recent studies have been done that suggest that mixed light touch manual therapies for those active-duty soldiers experiencing chronic PTSD may be helpful in reducing some of the symptoms of PTSD among those with head injuries (Davis et al., 2016).

Another physical therapy treatment avenue being studied is the use of complex manual therapy (CMT) for chronic low back pain in individuals who are survivors of torture. Initial findings indicate that it reduces back pain and thereby contributes to functional recovery. The treatment can also be considered to have positive effects on the musculoskeletal system of torture survivors as they age. In this study CMT was performed twice a week for 8 weeks and included:

  • Myofascial release to release muscle tension
  • Muscle energy techniques to release tension in the hamstring and gluteus maximus
  • Exercises to mitigate hypertension and pain in the lower back that include:
    • Pelvic posterior tilt exercise
    • Upper abdominal exercises
    • Lumbar stabilization exercise
    • Extension exercise for muscle strength by bridge exercise with a sling
    • Self exercise
    (Kim & Yu, 2015)


Studies indicate that cognitive-behavioral therapies have greater effects in improving PTSD symptoms than medications. Some individuals, however, may prefer medications or may benefit from receiving a medication in addition to psychotherapy. The medications prescribed for treating PTSD symptoms act on neurotransmitters related to the fear and anxiety circuitry of the brain, including serotonin, norepinephrine, GABA, and dopamine, among many others (Jeffreys, 2016).

Drug therapies have been generally most effective in decreasing the symptoms of hyperarousal and mood (irritability, anger, depression) and somewhat less effective for the symptoms of re-experiencing, emotional numbing, and behavioral avoidance (Stein, 2017).


The two FDA-approved medications for PTSD are sertraline (Zoloft) and paroxetine (Paxil). They belong to the class of antidepressants known as selective serotonin reuptake inhibitors (SSRIs). (Serotonin is important in regulating mood, anxiety, appetite, sleep, as well as other bodily functions.) SSRIs are the first-line medications for treatment of PTSD.

Besides the two FDA-approved SSRIs, there is strong evidence to support the use of two other antidepressants: the SSRI fluoxetine (Prozac) and the serotonin norepinephrine reuptake inhibitor (SNRI) venlafaxine (Effexor ER), used in the treatment of depression and anxiety (Jeffreys, 2016; Stein, 2017).

Currently there is insufficient evidence of the effectiveness of other antidepressants such as tricyclics, monoamine oxidase inhibitors, serotonin modulators (e.g., trazodone) or atypical antidepressants (e.g., mitazapine) for PTSD (Stein, 2017).


Currently there are only two medications approved by the FDA for treatment of PTSD. All other uses of medications prescribed for treatment of PTSD are “off label,” which means the medication is being used in a manner not specified in the FDA’s approved packaging label or insert. This label includes a written report that provides detailed instructions regarding approved uses and doses, which are based on the results of clinical studies that the drug maker submitted to the FDA (Jeffreys, 2016).


Anticonvulsant or anti-epileptic medications with mood-stabilizing properties have been studied for potential benefit for the symptoms of impulsive behavior, hyperarousal, and flashbacks, but findings at this point have been mostly negative (Stein, 2017; Jeffreys 2016).


SGAs are used only in patients who experienced a minimal or partial response to an SSRI or SNRI. Atypical antipsychotics are not recommended as monotherapy for PTSD. If other medications are ineffective, adjunctive treatment with quetiapine (Seroquel) or risperidone (Risperdal) may be prescribed (Stein, 2017). At this time, SGAs are recommended as treatment for co-occurring psychotic symptoms and mood disorders in PTSD (Jeffreys, 2016).


The alpha-adrenergic receptor blocker prazosin (Minipres) has been found to reduce nightmares and improve sleep by reducing the level of activating neurochemicals in the brain. It is believed to depress neurological pathways that are overstimulated in persons with PTSD (Jeffreys, 2016).


Benzodiazepines are frequently used but have rarely been studied for use in patients with PTSD. Drugs such as clonazepam (Klonopin) and alprazolam (Xanax) are used in PTSD patients for the short-term to relieve anxiety or insomnia. They do not work on the core symptoms of PTSD. Careful use is recommended, as these drugs can cause disinhibition, difficulty integrating the traumatic experience, and interference with the mental processes required to benefit from psychotherapy. They also have the potential for misuse and addiction (Jeffreys, 2016).


Identified goals and outcomes serve as a basis for evaluating the effectiveness of interventions for survivors of PTSD. The primary outcome is symptom reduction. This is evaluated using clinician-rated and self-reported measures that address the symptoms the patient presented with, and asks if they have lessened, remained the same, or increased. Other goals to be evaluated include:

  • Have comorbid medical or psychiatric conditions been prevented or reduced?
  • Has there been a remission of all symptoms?
  • Has the patient’s quality of life improved?
  • Has the patient effectively dealt with disability/functional impairment?
  • Has the patient returned to work or to active duty?

Alex  (continued)

Six months after he began treatment, Alex meets with his healthcare provider. In evaluating his treatment, she determines that he has achieved the following goals:

  • He no longer has thoughts of suicide.
  • His symptoms have lessened to a great extent, and most days he is functioning well.
  • He has not reported any signs or symptoms of depression or anxiety.
  • His sleep has improved, and most nights he sleeps undisturbed for 6 to 7 hours.
  • He no longer feels angry and has not had any outbursts for over 3 months.
  • Alex has returned to his wife, and they are now involved in family counseling.
  • He is able to talk about the loss of his friend and recognizes he was not to blame for his death.
  • Although he continues to have a drink now and then, he has refrained from abusing alcohol or other substances.
  • Alex reports he still has memories of the trauma, but he no longer responds physiologically to them. Emotionally he says that he “just feels sad” when he remembers.
  • Last month he returned to his former place of employment as a part-time dispatcher. As he continues to improve, he is hopeful that he can once again work in the department as a firefighter.


Review of the literature addressing the issue of PTSD prevention reveals that, despite its critical importance, the prevention of PTSD is under-researched and inappropriately explored and that the majority of interventions used to prevent PTSD are supported by weak evidence (Qi et al., 2016).

The following is a summary of the methods being studied for their effectiveness and the results of the findings to date.

Psychological Interventions


Debriefing refers to a variety of practices intended to provide emotional and psychological support immediately following a traumatic event, the goal being the prevention of development of PTSD and other negative long-tem consequences. There are three types of debriefing:

  • Operational Debriefing: A routine and formal part of an organizational response to a disaster; may help survivors acquire an overall sense of meaning and a degree of closure
  • Critical Incident Stress Debriefing: A formalized, structured method whereby a group of rescue and response workers reviews the stress experience of disaster
  • Psychological Debriefing: A single session, which may last between one and three hours, in the days immediately following a traumatic event

Debriefing as currently employed may be useful for low-magnitude stress exposure and symptoms or for emergency care providers. However, there is no evidence that debriefing reduces the risk of PTSD, depression, or anxiety, or reduces psychiatric symptoms. In long-term follow-up studies, however, psychological debriefing has been shown to have some negative harmful effects that increase stress or complicate recovery (Lake, 2017; Qi et al., 2016; Litz & Gray, 2016; NCPTSD, 2016).


Based upon limited evidence, brief trauma-focused CBT may be the most effective intervention for reducing PTSD symptom severity following exposure to trauma, and collaborative care may reduce the symptoms of PTSD symptoms following injury, but it does not prevent the development of PTSD.

CBT is currently the mainstay of attempts at primary prevention of PTSD. Studies have found that CBT is most effective for sexual assault victims; however, it has a marginal effect among accident victims and was not effective for victims of physical assault.

It is important to note that early CBT leaves numerous survivors unimproved and requiring other interventions such as cognitive therapy, prolonged exposure therapy, psychoeducation, pharmacotherapy, and supportive counseling. At this time, however, CBT is considered a “must try” in symptomatic trauma survivors and may shorten symptom duration by months or even years (Lake, 2017; Qi et al., 2016).

Currently there is no evidence to support the routine implementation of any type of psychological intervention to all individuals following trauma in an effort to prevent the development of PTSD (Lake, 2017; Qi et al., 2016).

Pharmacological Interventions

Various pharmacological agents have been examined to determine their effectiveness in the prevention of PTSD symptoms.

  • Hydrocortizone: There is only moderate-quality evidence for its effectiveness, especially in patients who have never been treated for psychiatric disorders. The underlying mechanism has not yet been established.
  • Propranolol: This beta-adrenergic antagonist showed some promise in reducing physiological responses to mental imagery of traumatic events three months after the event but did not reduce PTSD symptoms. All other studies to date have failed to show a preventive effect for propranolol.
  • Benzodiazepines: Benzodiazepines are known to interfere with learning and were believed capable of reducing excessive trauma-related learning. However, to date, clinical trials of benzodiazepines for use in preventing PTSD symptoms have had negative findings. Patients given benzodiazepines were three times more likely to have PTSD at six months. Further research and evidence is clearly indicated, including the use of benzodiazepines to affect traumatic recall within minutes or hours from trauma exposure.
  • Morphine: Early studies suggest that morphine can produce retrograde amnesia for a conditioned fear in patients experiencing pain. Pain after trauma exposure is a potent predictor of PTSD. It is unclear, however, whether morphine has any preventive value in trauma survivors without physical pain.
    (Lake, 2017; Qi et al., 2016)

Currently, there are no pharmacological agents that can be recommended for the prevention of PTSD. Researchers continue to probe for answers and develop ways to prevent or reduce the severity of PTSD symptoms.


The American Psychiatric Association created the PTSD diagnosis in 1980, and since then it has been the subject of much ongoing study and research. Evidence shows that there are numerous and variable situations that can lead to the development of PTSD as well as a variable time span in which the disorder may make itself known. There is yet much to be learned about this complex disorder and how best to treat it. It is important, however, that healthcare professionals, regardless of the specialty or clinical situation in which they work, have a baseline understanding of how this disorder presents and the most current interventions available to both patients and support persons.


NOTE: Complete URLs for references retrieved from online sources are provided in the PDF of this course.

Aceto P & Lai P. (2016). PTSD after anesthesia: prevalence, diagnosis, and proposed treatments. Comprehensive Guide to Post-Traumatic Stress Disorders. Switzerland: Springer International Publishing.

American Occupational Therapy Association (AOTA). (2015). Occupational therapy’s role in posttraumatic stress disorder. Retrieved from

American Psychiatric Association (APA). (2013). Diagnostic and statistical manual of mental disorders (DSM-5) (5th ed.). Washington, DC: Author.

American Psychological Association (APA). (2017a). The road to resilience. Retrieved from

American Psychological Association (APA). (2017b). Clinical practice guidelines for the treatment of posttraumatic stress disorder (PTSD) in adults. Retrieved from

Arenson M & Cohen B. (2017). Posttraumatic stress disorder and cardiovascular disease. PTSD: Research Quarterly, 28(1). Retrieved from

Bassett D, Buchwald D, & Manson S. (2014). Posttraumatic stress disorder and symptoms among American Indians and Alaska Natives: a review of the literature. Soc Psychiatry Psychiatr Epidemiol, 49(3), 417–33.

British Columbia Children’s Hospital (BCCH). (2017). Post-traumatic stress disorder. Retrieved from

Carlson E & Ruzek J. (2016). PTSD and the family. Retrieved from

Cohen J. (2017). Psychosocial interventions for posttraumatic stress disorder in children and adolescents. UpToDate. Retrieved from

Comer J, Dantowitz A, Chou T, Edson A, Eklins M, Kerns C, et al. (2014). Adjustment among area youth after the Boston Marathon bombing and subsequent manhunt. Retrieved from

Czeh B & Fuchs E. (2016). Remodeling of neural networks by stress. In G Fink (Ed.), Stress: concepts, cognition, emotion and behavior: handbook of stress, vol. 1, pp. 117–24. London: Elsevier.

Davis L, Hanson B, & Gilliam S. (2016). Pilot study of the effects of mixed light touch manual therapies on active duty soldiers with chronic post-traumatic stress disorder and injury to the head. J BodyW Mov Ther, 20(1), 42–51. doi:10.1016/j.jbmt.2015.03.006

DeCarvalho L. (2016). The experience of chronic pain and PTSD: a guide for health care providers. Retrieved from

Encyclopedia of Mental Disorders. (2017). Mental disorders. Retrieved from

Evens-Campell T. (2008). Historical trauma in American Indian/Native Alaska communities. Journal of Interpersonal Violence, 23(3), 316–38.

Gradus J. (2017). Epidemiology of PTSD. Retrieved from

Haagen J, Heide F, Mooren T, Knipscheer J, & Kleber R. (2017). Predicting post-traumatic stress disorder treatment response in refugees: multilevel analysis. British Journal of Clinical Psychology, 56(1), 69–83.

Hamblen J. (2017). ) PTSD 101: PTSD overview. Retrieved from

Hamblen J & Barnett E. (2016). PTSD in children and adolescents. Retrieved from

Hamblen J, Schnurr P, Rosenberg A, & Eftekhari A. (2017). Overview of psychotherapy for PTSD. Retrieved from

Hardy A & Brown-Rice K. (2016). Violence and residual associations among Native Americans living on tribal lands. The Professional Counselor, 6(4), 328–43.

Hermann B. (2017). PTSD assessment and treatment in older adults. Retrieved from

Hout M & Engelhard I. (2012). How does EMDR work? Journal of Experimental Psychopathology, 3(5), 724–38.

Hudenko W, Homaifar B, & Wortzel H. (2017). The relationship between PTSD and suicide. Retrieved from

Jankowski K. (2016). PTSD and physical health. Retrieved from

Jeffreys M. (2016). Clinicians’ guide to medications for PTSD. Retrieved from

Jones E. (2005). Shell shock to PTSD: military psychiatry from 1900 to the gulf war (Maudsley Monograph). New York: Psychology Press.

Kaiser A, Wachen J, Potter C, Moye J, & Davison E. (2017). Posttraumatic stress symptoms among older adults: a review. Retrieved from

Kim H & Yu S. (2015). Effects of complex manual therapy on PTSD, pain, function, and balance of male torture survivors with chronic low back pain. J Phys Ther Sci, 27(9). doi:10.1589/jpts.27.2763.

Lake J. (2017). Preventing PTSD after trauma. Retrieved from

Lamprecht F & Sack M. (2002). Posttraumatic stress disorder revisited. Psychosom Med, 64(2), 222–37.

Lazarony L. (2016). Post-stroke PTSD. National Stroke Association.Retrieved from

Litz B & Gray M. (2016). Early intervention for trauma: current status and future directions. Retrieved from

McLaughlin K. (2016). Posttraumatic stress disorder in children: epidemiology, pathogenesis, clinical manifestations, course, assessment, and diagnosis. UpToDate. Retrieved from

Matosin N & Cruceanu C. (2017). Stress-related memory impairments are modulated by the synergistic action of stress hormones: implications for PTSD. Journal of Neuroscience, 37(16), 4225–7. doi:

Mayo Clinic. (2017). Post-traumatic stress disorder (PTSD). Retrieved from

NANDA International, Inc. (2014). Nursing diagnoses: definitions and classification, 2015–17. Philadelphia: Wiley Blackwell.

National Center for PTSD (NCPTSD). (2017a). Treatment of co-occurring PTSD and substance use disorder in VA. Retrieved from

National Center for PTSD (NCPTSD). (2017b). Life events checklist for DSM-5 (LEC-5). Retrieved from

National Center for PTSD (NCPTSD). (2017c). Cognitive processing therapy for PTSD. Retrieved from

National Center for PTSD (NCPTSD). (2016). Types of debriefing following disasters. Retrieved from

National Center for PTSD (NCPTSD). (2015a). Depression, trauma, and PTSD. Retrieved from

National Center for PTSD (NCPTSD). (2015b). Helping a family member who has PTSD. Retrieved from

National Center for PTSD (NCPTSD). (2011). Treatment for PTSD. Retrieved from

National Institute of Mental Health (NIMH). (2016). Post-traumatic stress disorder. Retrieved from

National Veterans Foundation (NVF). (2015). Focusing on a solution for PTSD in women veterans. Retrieved from

Nickels N, Kubicki K, & Maestripieri D. (2017). Sex differences in the effects of psychosocial stress on cooperative and prosocial behavior: evidence for “flight or fight” in males and “tend and befriend” in females. Adaptive Human Behavior and Physiology, 3(2), 171–83. doi:10.1007/s40750-017-0062-3

Nursey J & Phelps A. (2016). Stress, trauma, and memory in PTSD. In G Fink (Ed.), Stress: concepts, cognition, emotion and behavior: handbook of stress, vol. 1, pp. 160–75. London: Elsevier.

Oshberg F. (2017). When helping hurts. Retrieved from

Parker A, Sricharoenchai T, Raparla S, Schneck K, Bienvenu O, & Needham D. (2015). Posttraumatic stress disorder in critical illness survivors: a meta-analysis. Critical Care Medicine, 43(5), 1121–9. doi:10.1097/CCM.0000000000000882

Pukay-Martin N, Fredman S, & Monson C. (2016). Couple therapy for posttraumatic stress disorder. In Ainspan N , Bryan C & Penk W (Eds.), Handbook of psychosocial interventions for veterans and service members, ch. 26, New York: Oxford University Press.

Qi W, Gevonden M, & Shaley A. (2016). Prevention of post-traumatic stress disorder after trauma: current evidence and future directions. Curr Psychiatry Rep, 18(20). doi:10.1007/s11920-015-0655-0

Rothbaum B. (2017). Psychotherapy for posttraumatic stress disorder in adults. UpToDate. Retrieved from

Sareen J. (2017). Posttraumatic stress disorder in adults: epidemiology, pathophysiology, clinical manifestations, course, assessment and diagnosis. UpToDate. Retrieved from

Selye H. (1991). The stress of life (rev. ed.). New York: McGraw-Hill.

Scheeringa M. (2016). PTSD for children 6 years and younger. Retrieved from

Sippel L, Allington C, Pietrzak R, Harpaz-Rotem I, Mayes L, & Olff M. (2017). Oxytocin and stress-related disorders. Sage Journals. Retrieved from

Stein M. (2017). Pharmacotherapy for posttraumatic stress disorder adults. UpToDate. Retrieved from

Strauss J, Lang A, & Schnurr P. (2017) Complementary and alternative medicine (CAM) for PTSD. Retrieved from

The British Medical Journal: Best Practice (The BMJ). (2017). Post-traumatic stress disorder: pathophysiology. Retrieved from

Trimble M. (1981). Posttraumatic neurosis, from railway spine to the whiplash. Chichester: John Wiley.

Tull M. (2017). The connection between PTSD and suicide. Retrieved from

Tulloch H, Greenman P, & Tasse V. (2015). Post-traumatic stress disorder among cardiac patients: prevalence, risk factors, and considerations for assessment and treatment. Behav Sci (Basel), 5(1), 27–40. doi:10.3390/bs5010027

Varcarolis E. (2015). Manual of psychiatric nursing care planning: assessment guides, diagnosis, and psychopharmacology (5th ed.). St. Louis: Saunders.

Veith C. (1965). Hysteria: the history of a disease. Chicago: University of Chicago Press.

Veterans and PTSD. (2015). Veterans statistics: PTSD, depression, TBI, suicide. Retrieved from

Vogt D. (2017). Research on women, trauma, and PTSD. Retrieved from

Wang Z & Young R. (2016). PTSD: a disorder with an immunological component. Front Immunol, 7, 219. doi:10.3389/fimmu.2016.00219

Yoder M & Norman S. (2016). Co-occurring PTSD and neurocognitive disorder (NCD). Retrieved from

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